PIAS1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD83466A
Immunofluorescence analysis of GFP-RNF168 transgenic U2OS cells using PIAS1 Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using PIAS1 Polyclonal Antibody
Product Name
PIAS1 Polyclonal Antibody
Catalog Number
RD83466A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human PIAS1 (NP_057250.1).
Gene ID
8554
Swissprot
O75925
Synonyms
PIAS1DDXBP1GBPGU/RH-IIZMIZ3
Applications
Reactivity
Human,Mouse
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas