PIM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75554A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PIM1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PIM1 Polyclonal Antibody at dilution 1:40
Product Name
PIM1 Polyclonal Antibody
Catalog Number
RD75554A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Immunogen Information
Immunogen
Recombinant protein of human PIM1
Swissprot
P11309
Synonyms
Oncogene PIM 1Oncogene PIM1PIM 1pim 1 kinase 44 kDa isoformPim 1 kinasepim 1 oncogene (proviral integration site 1)Pim 1 oncogenePIMPIM1pim1 kinase 44 kDa isoformPIM1Pim2PIM3Proto oncogene serine/threonine protein kinase Pim 1Proto-oncogene
Gene Accession
BC020224
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.