This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen Information
Immunogen
Synthetic peptide of human PIP5K1C
Swissprot
O60331
Synonyms
Diphosphoinositide kinaseLCCS3Phosphatidylinositol-4-phosphate 5-kinase type I gammaPhosphatidylinositol-4-phosphate 5-kinase type-1 gammaPI51CPI51CPIP5K GAMMAPIP5K1-gammaPip5k1cPIP5KIgammaPtdIns(4)P 5 kinase gammaPtdIns(4)P-5-kinase 1 gammaTy
Calculated MW
73 kDa
Gene Accession
NP_036530
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4