PKLR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87453A
Western blot analysis of extracts of various cell lines using PKLR Polyclonal Antibody at 1:3000 dilution.
Product Name
PKLR Polyclonal Antibody
Catalog Number
RD87453A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human PKLR
Gene ID
5313
Swissprot
P30613
Synonyms
PKLRPK1PKLPKRPKRLRPK
Calculated MW
22kDa
Observed MW
26kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.