PKLR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD267386A
Immunohistochemistry of paraffin-embedded Human normal breast using PKLR Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human normal colon using PKLR Polyclonal Antibody at dilution of 1:200 (40x lens).
Product Name
PKLR Polyclonal Antibody
Catalog Number
RD267386A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human PKLR (NP_000289.1).
Gene ID
5313
Swissprot
P30613
Synonyms
PKLRPK1PKLPKRPKRLRPK
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas