This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Immunogen Information
Immunogen
Recombinant protein of human PKM2
Swissprot
P14618
Synonyms
CTHBPCytosolic thyroid hormone binding proteinCytosolic thyroid hormone-binding proteinKPYMMGC3932OIP 3OIP-3OIP3OPA interacting protein 3Opa-interacting protein 3p58PK muscle typePKmuscle typePK2PK3PKMPKM2pykmPyruvate kinase 2/3Pyruvat
Calculated MW
58 kDa
Gene Accession
BC007640
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4