PKM2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90715A
Western blot with PKM2 Polyclonal Antibody at dilution of 1:1000.lane 1:JurKat whole cell lysate
Product Name
PKM2 Polyclonal Antibody
Catalog Number
RD90715A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP,generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein,a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells,suggesting a role of this protein in bacterial pathogenesis.
Immunogen Information
Immunogen
Recombinant Human PKM2 Protein expressed by E.coli
Swissprot
P14618
Synonyms
Pyruvate kinase PKMCytosolic thyroid hormone-binding proteinOpa-interacting protein 3Pyruvate kinase 2/3Pyruvate kinase muscle isozymeThreonine-protein kinase PKM2Thyroid hormone-binding protein 1 (THBP1)PKMOIP3PK2PK3PKM2
Calculated MW
24 kDa
Observed MW
24 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.