Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes.
Immunogen Information
Immunogen
Synthetic peptide of human PLEC
Swissprot
Q15149
Synonyms
EBS1EBSOHD1Hemidesmosomal protein 1PCNpleCPLECPLEC1PLEC1bPlectin 1Plectin 1 intermediate filament binding protein 500kDaPlectin 6PlectinPlectin-1PLTN
Gene Accession
NP_000436
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4