May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
Immunogen Information
Immunogen
Fusion protein of human PLEKHF2
Swissprot
Q9H8W4
Synonyms
110070J07RikAA673237FLJ13187PH and FYVE domain containing protein 2PH and FYVE domain-containing protein 2PH domain containing family F member 2PH domain-containing family F member 2Phafin 2Phafin-2PHAFIN2PKHF2pleckstrin homology domain contain