Pleckstrin homology domain-containing family O member 1is aproteinthat in humans is encoded by thePLEKHO1gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.
Immunogen Information
Immunogen
Recombinant protein of human PLEKHO1
Swissprot
Q53GL0
Synonyms
C-Jun-binding proteinCasein kinase 2-interacting protein 1CK2 interacting protein 1CK2 interacting protein 1 HQ0024c proteinCK2-interacting protein 1CKIP 1CKIP-1CKIP1JBPOC120Osteoclast maturation associated gene 120 proteinOsteoclast maturation
Calculated MW
46 kDa
Gene Accession
BC010149
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4