The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.
Immunogen Information
Immunogen
Synthetic peptide of human PPAP2A
Swissprot
O14494
Synonyms
Lipid phosphate phosphohydrolase 1Lipid phosphate phosphohydrolase 1aLLP1aLPP1LPP1PAP 2aPAP-2aPAP2PAP2-alphaPAP2aPAP2a2PAP2alpha2PAPalpha1Phosphatidate phosphohydrolase type 2aPhosphatidic acid phosphatase 2aPhosphatidic acid phosphatase ty
Calculated MW
32 kDa
Gene Accession
NP_003702
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4