Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculatureBy similarity. Mediates anti-angiogenic signaling in response to SEMA3E.
Immunogen Information
Immunogen
Synthetic peptide of human PLXND1
Swissprot
Q9Y4D7
Synonyms
KIAA0620MGC75353PLEX D1PLEXD 1PLEXD1Plexin-D1PlexinD1PLXD1PLXN D1PLXND 1PLXND1PLXND1 protein
Calculated MW
212 kDa
Gene Accession
NP_055918
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4