3'-exoribonuclease that has a preference for poly(A tails of mRNAs, thereby efficiently degrading poly(A tails. Exonucleolytic degradation of the poly(A tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells (By similarity.
Immunogen Information
Immunogen
Recombinant fusion protein of human PNLDC1
Gene ID
154197
Swissprot
Q8NA58
Synonyms
HsPNLDC1PNLDC1
Calculated MW
22kDa/33kDa
Observed MW
35KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.