PNPO Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219759A
Western blot analysis of 293T cell lysates using PNPO Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human brain tissue using PNPO Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PNPO Polyclonal Antibody at dilution of 1:30(×200)
Product Name
PNPO Polyclonal Antibody
Catalog Number
RD219759A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Immunogen Information
Immunogen
Synthetic peptide of human PNPO
Swissprot
Q9NVS9
Synonyms
EC 1.4.3.5FLJ10535PDXPOPNPOPNPOPyridoxal 5' phosphate synthasepyridoxamine 5' phosphate oxidasePyridoxamine phosphate oxidasePyridoxamine-phosphate oxidasepyridoxine 5' phosphate oxidasePyridoxine-5'-phosphate oxidase
Calculated MW
30 kDa
Observed MW
Refer to figures
Gene Accession
NP060599
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas