PNPO Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunofluorescence analysis of L929 cells using PNPO Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using PNPO Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using PNPO Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using PNPO Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Overview

Circle
Product Name
PNPO Polyclonal Antibody
Catalog Number
RD267361A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Immunogen Information

Circle
Immunogen
Recombinant protein of human PNPO.
Gene ID
55163
Swissprot
Q9NVS9
Synonyms
HEL-S-302PDXPOPNPO

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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