PNPO Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD267361A
Immunofluorescence analysis of L929 cells using PNPO Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using PNPO Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using PNPO Polyclonal Antibody at dilution of  1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using PNPO Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Overview

Circle
Product Name
PNPO Polyclonal Antibody
Catalog Number
RD267361A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Immunogen Information

Circle
Immunogen
Recombinant protein of human PNPO.
Gene ID
55163
Swissprot
Q9NVS9
Synonyms
HEL-S-302PDXPOPNPO

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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