PON3/paraoxonase 3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blotting with anti-PON3 polyclonal antibody at dilution of 1:1000. Lane 1: Rat liver lysate, lane 2: Mouse kidney lysate(Negative control), lane 3: Mouse liver lysate.
Product Name
PON3/paraoxonase 3 Polyclonal Antibody
Catalog Number
RD86662A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The paraoxonase (PON) gene family of antioxidant enzymes includes three known members located adjacent to each other on chromosome 7. Paraoxonase/lactonase 3 (PON3) is a 354 amino acid, 39.6 kDa protein that is secreted into the bloodstream and associates with high-density lipoprotein (HDL). PON3 has lactonase activity (EC 3.1.1) and rapidly hydrolyzes lactones. PON3 exhibits no paraoxonase and very limited arylesterase activities. PON3 is an important antioxidant and can inhibit the oxidation of low-density lipoprotein (LDL), a function that may slow the initiation and progression of atherosclerosis.
Immunogen Information
Immunogen
Recombinant Human PON3 protein expressed by E.coli.
Gene ID
5446
Swissprot
Q15166
Synonyms
Serum paraoxonase/lactonase 3PON3
Calculated MW
21kDa
Observed MW
21kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
2mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol,pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas