This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse PPARγ
Swissprot
P37231,P37238,O88275
Synonyms
CIMT1GLM1NR1C3Nuclear receptor subfamily 1 group C member 3OTTHUMP00000185032OTTHUMP00000185036Peroxisome proliferator activated nuclear receptor gamma variant 1Peroxisome proliferator activated receptor gamma 1Peroxisome Proliferator Activated Re
Calculated MW
58Da
Observed MW
50-60 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.58 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4