PPM1B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252842A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PPM1B Polyclonal Antibody at dilution of 1:50(×200)
Product Name
PPM1B Polyclonal Antibody
Catalog Number
RD252842A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Immunogen Information
Immunogen
Fusion protein of human PPM1B
Swissprot
O75688
Synonyms
MGC21657OTTHUMP00000158953OTTHUMP00000158954OTTHUMP00000158955OTTHUMP00000202394OTTHUMP00000202395OTTHUMP00000202399PP2C betaPP2C beta XPP2C-betaPP2CBPP2CbetaPPC2BETAXPPM 1BPpm1bPPM1BProtein phosphatase 1B (formerly 2C) magnesium dependent
Gene Accession
BC012002
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.44 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas