PPM1F Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79249A
Western Blot analysis of K562 cell and Human fetal liver tissue using PPM1F Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PPM1F Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human colon cancer using PPM1F Polyclonal Antibody at dilution of 1:40
Product Name
PPM1F Polyclonal Antibody
Catalog Number
RD79249A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Immunogen Information
Immunogen
Synthetic peptide of human PPM1F
Swissprot
P49593
Synonyms
Ca(2+)/calmodulin-dependent protein kinase phosphataseCaM-kinase phosphataseCAMKPCaMKPaseFEM 2hFEM-2KIAA0015Partner of PIX 2POPX2PP2C phosphatasePpm1fPPM1FProtein fem-2 homologProtein phosphatase 1F (PP2C domain containing)Protein phosphatas
Calculated MW
50 kDa
Gene Accession
NP_055449
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas