PPP1R12A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75992A
Western Blot analysis of A172 cell using PPP1R12A Polyclonal Antibody at dilution of 1:450
Product Name
PPP1R12A Polyclonal Antibody
Catalog Number
RD75992A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.
Immunogen Information
Immunogen
Recombinant protein of human PPP1R12A
Swissprot
O14974
Synonyms
M130MBSMyosin binding subunitMyosin phosphatase target subunit 1Myosin phosphatase targeting subunit 1Myosin phosphatase-targeting subunit 1MYPT1MYPT1PPP1R12AProtein phosphatase 1 regulatory inhibitor subunit 12AProtein phosphatase 1 regulatory
Calculated MW
115 kDa
Gene Accession
BC111752
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas