PPP1R13L Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78546A
Western Blot analysis of MCF7 and hela cell using PPP1R13L Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using PPP1R13L Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer using PPP1R13L Polyclonal Antibody at dilution of 1:30
Product Name
PPP1R13L Polyclonal Antibody
Catalog Number
RD78546A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
Immunogen Information
Immunogen
Synthetic peptide of human PPP1R13L
Swissprot
Q8WUF5
Synonyms
IASPPinhibitor of apoptosis stimulating protein of p53Inhibitor of ASPP proteinNFkB interacting protein 1NKIP1PPP1R13B-like proteinPPP1R13LProtein iASPPprotein phosphatase 1 regulatory (inhibitor) subunit 13 likeRAIRelA-associated inhibitor
Calculated MW
89 kDa
Gene Accession
NP_006654
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas