This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human PPP1R1B
Swissprot
Q9UD71
Synonyms
DARPP 32DARPP-32Dopamine and cAMP regulated neuronal phosphoprotein 32Dopamine and cAMP regulated neuronal phosphoproteinDopamine and cAMP regulated phosphoproteinDopamine and cAMP regulated phosphoprotein DARPP 32Dopamine and cAMP regulated phospho
Gene Accession
BC001519
Applications
Reactivity
Human,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4