PRAME Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252200A
Immunohistochemistry of paraffin-embedded Human brain tissue using PRAME Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PRAME Polyclonal Antibody at dilution of 1:65(×200)
Product Name
PRAME Polyclonal Antibody
Catalog Number
RD252200A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human PRAME
Swissprot
P78395
Synonyms
4930534P07RikCancer/testis antigen 130CT130MAPEMelanoma antigen preferentially expressed in tumorsOIP 4OIP-4OIP4OPA interacting protein 4Opa interacting protein OIP4OPA-interacting protein 4PRAMEPRAMEPreferentially expressed antigen in melan
Gene Accession
BC014074
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:250, ELISA 1:5000-1:10000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas