Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
Immunogen Information
Immunogen
Synthetic peptide of human PRKAR1B
Swissprot
P31321
Synonyms
cAMP dependent protein kinase type I beta regulatory subunitcAMP-dependent protein kinase type I-beta regulatory subunitKAP1PKARI betaPRKAR 1PRKAR 1BPRKAR1Prkar1bPRKAR1B proteinProtein kinase cAMP dependent regulatory type I betaRIbeta
Calculated MW
43 kDa
Gene Accession
NP_001158230
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4