PRMT7 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75329A
Western Blot analysis of Human liver cancer tissue using PRMT7 Polyclonal Antibody at dilution of 1:500
Product Name
PRMT7 Polyclonal Antibody
Catalog Number
RD75329A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).
Immunogen Information
Immunogen
Recombinant protein of human PRMT7
Swissprot
Q9NVM4
Synonyms
[Myelin basic protein]-arginine N-methyltransferase PRMT7ANM7FLJ10640Histone-arginine N-methyltransferase PRMT7KIAA1933Myelin basic protein arginine N methyltransferaseOTTHUMP00000174863PRMT7Protein arginine methyltransferase 7Protein arginine N-
Calculated MW
78 kDa
Gene Accession
BC000146
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas