This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.
Immunogen Information
Immunogen
Recombinant protein of human PROS1
Swissprot
P07225
Synonyms
Preproprotein SPropiece of latent protein SPROS 1PROSPROSproS1Protein S alphaProtein SaPS 21PS 22PS 23PS 24PS 25PS 26PS21PS22PS23PS24PS25PS26PSATHPH5THPH6Vitamin K dependent protein SVitamin K-dependent plasma protein SVitamin K-d
Gene Accession
BC015801
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4