Proteinase 3/PR3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD88845A
Western blot analysis of extracts of Rat lung using Proteinase 3/PR3 Polyclonal Antibody at 1:1000 dilution.
Product Name
Proteinase 3/PR3 Polyclonal Antibody
Catalog Number
RD88845A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.
Immunogen Information
Immunogen
Recombinant fusion protein of human Proteinase 3/PR3
Gene ID
5657
Swissprot
P24158
Synonyms
ACPAAGP7C-ANCACANCAMBNMBTNP-4NP4P29PR-3PR3PRTN3
Calculated MW
92 kDa
Observed MW
110kDa
Applications
Reactivity
Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.