PRPF8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD217841A
Western blot analysis of 293T cell lysates using PRPF8 Polyclonal Antibody at dilution of 1:450
Product Name
PRPF8 Polyclonal Antibody
Catalog Number
RD217841A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Immunogen Information
Immunogen
Synthetic peptide of human PRPF8
Swissprot
Q6P2Q9
Synonyms
220 kDa U5 snRNP specific protein220 kDa U5 snRNP-specific proteinApoptosis regulated protein 1Apoptosis regulated protein 2HPRP8p220Pre mRNA processing factor 8Pre mRNA-processing factor 8S. cerevisiaehomolog ofPre-mRNA-processing-splicing fa
Calculated MW
274 kDa
Observed MW
Refer to figures
Gene Accession
NP006436
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas