Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Immunogen Information
Immunogen
Fusion protein of human PSD4
Swissprot
Q8NDX1
Synonyms
EFA6BExchange factor for ADP-ribosylation factor guanine nucleotide factor 6BFLJ36237FLJ37279PH and SEC7 domain-containing protein 4Pleckstrin homology and SEC7 domain-containing protein 4Ppleckstrin and Sec7 domain containing 4PSD4PSD4SEC7 homo