Western blot analysis of Hela cell Mouse spleen tissue Mouse liver tissue PC3 cell HL60 cell A549 cell NIH/3T3 cell lysates using PSMA3 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PSMA3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using PSMA3 Polyclonal Antibody at dilution of 1:50(×200)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Immunogen Information
Immunogen
Fusion protein of human PSMA3
Swissprot
P25788
Synonyms
HC8Macropain subunit C8MGC12306MGC32631Multicatalytic endopeptidase complex subunit C8Proteasome (prosome macropain) subunit alpha type 3Proteasome alpha 3 subunitProteasome component C8Proteasome subunit alpha type 3Proteasome subunit alpha typ