PTH1R Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90217A
Western blot analysis of extracts of various cell lines using PTH1R Polyclonal Antibody at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded Rat leg bone using PTH1R Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Variation
Quantity
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Overview
Product Name
PTH1R Polyclonal Antibody
Catalog Number
RD90217A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human PTH1R
Gene ID
5745
Swissprot
Q03431
Synonyms
PTH1RPFEPTHRPTHR1
Calculated MW
29kDa
Observed MW
25-35KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IHC 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas