PTPRJ Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD265741A
Western blot analysis of extracts of Raji cells using PTPRJ Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of Raji cells using PTPRJ Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
PTPRJ Polyclonal Antibody
Catalog Number
RD265741A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

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Immunogen
Recombinant fusion protein of human PTPRJ (NP_002834.3).
Gene ID
5795
Swissprot
Q12913
Synonyms
PTPRJCD148DEP1HPTPetaR-PTP-ETASCC1
Calculated MW
57 kDa/145 kDa
Observed MW
260 kDa

Applications

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Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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