PTPRN Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252202A
Immunohistochemistry of paraffin-embedded Human brain tissue using PTPRN Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PTPRN Polyclonal Antibody at dilution of 1:55(×200)
Product Name
PTPRN Polyclonal Antibody
Catalog Number
RD252202A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
Immunogen Information
Immunogen
Fusion protein of human PTPRN
Swissprot
Q16849
Synonyms
CA 512FLJ16131IA 2IA 2/PTPIA2IA2/PTPICA 3ICA 512ICA3ICA512Islet cell antigen 2Islet cell antigen 512Islet cell autoantigen 3Protein tyrosine phosphatase like NProtein tyrosine phosphatase like N precursorProtein tyrosine phosphatase recepto
Gene Accession
BC007713
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas