Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.
Immunogen Information
Immunogen
Synthetic peptide of human PTX3
Swissprot
P26022
Synonyms
AI607804Pentaxin 3Pentaxin-related protein PTX3Pentraxin 3 longPentraxin-related genePentraxin-related gene rapidly induced by IL-1 betaPentraxin-related protein PTX3PTX3PTX3TNF alpha-induced protein 5TNFAIP5TSG-14TSG14Tumor necrosis factor a
Calculated MW
42 kDa
Gene Accession
NP_002843
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4