Purified Anti-Human CD22 Antibody[HIB22]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30712F
Product Name
Purified Anti-Human CD22 Antibody[HIB22]
Catalog Number
RD30712F
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
Immunogen Information
Gene ID
933
Synonyms
B-cell receptor CD22Cd22B-lymphocyte cell adhesion moleculeBL-CAMSialic acid-binding Ig-like lectin 2Siglec-2T-cell surface antigen Leu-14CD22Lyb-8Siglec2
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
Unconjugated
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.