Purified Anti-Human CD45RA Antibody[HI100]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30586F
Product Name
Purified Anti-Human CD45RA Antibody[HI100]
Catalog Number
RD30586F
Isotype
Mouse IgG2b, κ
Host
Mouse
Background
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/na?ve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Immunogen Information
Gene ID
5788
Synonyms
Receptor-type tyrosine-protein phosphatase CPtprcL-CALy-5T200CD45
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
Unconjugated
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.