PUS10 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77074A
Western Blot analysis of Mouse intestinum tenue tissue using PUS10 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human breast cancer using PUS10 Polyclonal Antibody at dilution of 1:45
Immunohistochemistry of paraffin-embedded Human brain using PUS10 Polyclonal Antibody at dilution of 1:45
Product Name
PUS10 Polyclonal Antibody
Catalog Number
RD77074A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.
Immunogen Information
Immunogen
Synthetic peptide of human PUS10
Swissprot
Q3MIT2
Synonyms
CCDC139Coiled coil domain containing 139Coiled coil domain containing protein 139Coiled-coil domain-containing protein 139DOBIFLJ32312MGC126729Pseudouridine synthase 10Pseudouridylate synthase 10Psi55 synthasepus10PUS10Putative tRNA pseudourid
Calculated MW
60 kDa
Gene Accession
NP_653310
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.