PYGL Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of 231 and PC3 cell using PYGL Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PYGL Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human brain using PYGL Polyclonal Antibody at dilution of 1:35
Product Name
PYGL Polyclonal Antibody
Catalog Number
RD76062A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
Immunogen Information
Immunogen
Recombinant protein of human PYGL
Swissprot
P06737
Synonyms
Glycogen phosphorylaseGlycogen phosphorylase LGlycogen phosphorylase liverGlycogen phosphorylase liver formGSD6Hers diseaseglycogen storage disease type VIliver formOTTHUMP00000233649OTTHUMP00000233651Phosphorylase glycogen liverPyglPYGL
Calculated MW
97 kDa
Gene Accession
BC082229
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas