QDPR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot analysis of Mouse liver tissue Mouse brain tissue Rat brain tissue Rat liver tissue and Human fetal liver tissue lysates using QDPR Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using QDPR Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using QDPR Polyclonal Antibody at dilution of 1:70(×200)
Product Name
QDPR Polyclonal Antibody
Catalog Number
RD252713A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Immunogen Information
Immunogen
Fusion protein of human QDPR
Swissprot
P09417
Synonyms
67 dihydropteridine reductaseDHPRDHPRDihydropteridine reductaseHDHPRHPRPKU2QdprQuinoid dihydropteridine reductaseSDR33C1Short chain dehydrogenase/reductase family 33Cmember 1
Calculated MW
26 kDa
Observed MW
Refer to figures
Gene Accession
BC000576
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas