QPRT Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87860A
Western blot analysis of extracts of various cell lines using QPRT Polyclonal Antibody at 1:3000 dilution.
Product Name
QPRT Polyclonal Antibody
Catalog Number
RD87860A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human QPRT
Gene ID
23475
Swissprot
Q15274
Synonyms
QPRTHEL-S-90nQPRTase
Calculated MW
60kDa/107kDa
Observed MW
107kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.