Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K (PubMed:24349490). May be involved in multiple neurite formation (By similarity).
Immunogen Information
Immunogen
Fusion protein of human RAB39A
Swissprot
Q14964
Synonyms
rab related GTP binding proteinRab-39Rab39RAB39ARAB39A member RAS oncogene familyRas related protein Rab39ARas-related protein Rab-39ARB39A