This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen Information
Immunogen
Synthetic peptide of human RAB6A
Swissprot
P20340
Synonyms
GTP binding protein RAB6A'GTP binding protein RAB6BOncogene RAB6Rab 6Rab GTPaseRab-6RAB6RAB6 member RAS oncogene familyRAB6ARAB6A member RAS oncogene familyRab6A variant 3RAB6A'RAB6ARAB6BRas related protein Rab 6ARas-related protein Rab-6A
Calculated MW
24 kDa
Gene Accession
NP_002860
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4