Immunofluorescence analysis of C6 cells using [KO Validated] Rac1/2/3 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts from wild type (WT) and TOLLIP knockdown (KD) 293T cells using TOLLIP Polyclonal Antibody at 1:500 dilution.
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.