RAC2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD253322A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using RAC2 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RAC2 Polyclonal Antibody at dilution of 1:60(×200)
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Overview

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Product Name
RAC2 Polyclonal Antibody
Catalog Number
RD253322A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.

Immunogen Information

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Immunogen
Synthetic peptide of human RAC2
Swissprot
P15153
Synonyms
EN 7EN-7EN7GXHSPC 022HSPC022p21 Rac 2p21 Rac2p21-Rac2p21Rac2RAC 2Rac2RAC2Ras related C3 botulinum toxin substrate 2 (rho familysmall GTP binding protein Rac2Ras related C3 botulinum toxin substrate 2Ras related C3 botulinum toxin substrate
Gene Accession
NP002863

Applications

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Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.02 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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