RAC2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD70129A
Immunohistochemistry of paraffin-embedded Human Tonsil tissue using RAC2 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human Tonsil tissue using RAC2 Polyclonal Antibody at dilution of 1:200
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Overview

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Product Name
RAC2 Polyclonal Antibody
Catalog Number
RD70129A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.

Immunogen Information

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Immunogen
Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien
Swissprot
P15153
Synonyms
EN 7GXHSPC 022HSPC022p21 Rac 2RAC 2Ras related C3 botulinum toxin substrate 2Ras related C3 botulinum toxin substrate 3 (rho familysmall GTP binding protein Rac2)Ras related C3 botulinum toxin substrate 3Rho family small GTP binding protein Rac

Applications

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Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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