RAD18 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD81408A
Immunofluorescence analysis of U2OS cells using RAD18 Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using RAD18 Polyclonal Antibody
Product Name
RAD18 Polyclonal Antibody
Catalog Number
RD81408A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Immunogen Information
Immunogen
Recombinant fusion protein of human RAD18 (NP_064550.3).
Gene ID
56852
Swissprot
Q9NS91
Synonyms
RAD18RNF73
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas