The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Immunogen Information
Immunogen
Recombinant protein of human RAMP3
Swissprot
O60896
Synonyms
Calcitonin receptor like receptor activity modifying protein 3CRLR activity modifying protein 3CRLR activity-modifying protein 3OTTHUMP00000159549OTTHUMP00000214279OTTHUMP00000214280Receptor (calcitonin) activity modifying protein 3Receptor (G prot
Gene Accession
BC022304
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4