RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis.
Immunogen Information
Immunogen
Recombinant Human GTP-binding nuclear protein Ran protein
Swissprot
P62826
Synonyms
Androgen receptor associated protein 24Androgen receptor-associated protein 24ARA 24ARA24Gsp1GTP binding nuclear protein RANGTP-binding nuclear protein RanGTPase RanGuanosine triphosphatase RanLPSOK/SW-cl.81ranRAN member RAS oncogene familyRA
Calculated MW
24 kDa
Observed MW
24 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.