RAP1A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77318A
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using RAP1A Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using RAP1A Polyclonal Antibody at dilution 1:45
Product Name
RAP1A Polyclonal Antibody
Catalog Number
RD77318A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Immunogen Information
Immunogen
Recombinant protein of human RAP1A
Swissprot
P62834
Synonyms
C21KGG-22KGTP-binding protein smg p21AKREV1RAP1ARAP1Amember of RAS oncogene familyRAP1ARas-related protein 1ARas-related protein Krev-1Ras-related protein Rap-1ASMGP21
Gene Accession
BC014086
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas