This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.
Immunogen Information
Immunogen
Recombinant protein of human RAP1B
Swissprot
P61224
Synonyms
GTP-binding protein smg p21BK-REVOK/SW-cl.11RAL1Brap1bRAP1B member of RAS oncogene familyRAP1BRas family small GTP binding protein RAP1BRAS related protein RAP1BRas-related protein Rap-1bSmall GTP binding protein
Calculated MW
21 kDa
Gene Accession
BC000176
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4